Biofilms
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Biofilm
A biofilm is an aggregate of microorganisms in which cells adhere to each other on a surface. These adherent cells are frequently embedded within a self-produced matrix of extracellular polymeric substance (EPS). Biofilm EPS, which is also referred to as slime (although not everything described as slime is a biofilm), is a polymeric conglomeration generally composed of extracellular DNA, proteins, and polysaccharides. Biofilms may form on living or non-living surfaces and can be prevalent in natural, industrial and hospital settings. The microbial cells growing in a biofilm are physiologically distinct from planktonic cells of the same organism, which, by contrast, are single-cells that may float or swim in a liquid medium.
Microbes form a biofilm in response to many factors, which may include cellular recognition of specific or non-specific attachment sites on a surface, nutritional cues, or in some cases, by exposure of planktonic cells to sub-inhibitory concentrations of antibiotics. When a cell switches to the biofilm mode of growth, it undergoes a phenotypic shift in behavior in which large suites of genes are differentially regulated.
View MoreCenter at Montana State University has been at the global forefront of biofilm research for 35 years (Montana State University)
Public Technologies | 22 Apr 2025) BOZEMAN - Biofilms, which are groupings of microbes encased inside self-produced slime, have likely existed since shortly after the dawn of life on Earth. In fact, some researchers theorize that these early communal conglomerations may have put the ooze in "primordial ooze" some 3.5 billion years ago. The world's...
Ultrasound-activated nanoparticles wipe out biofilm infections in lab tests
Phys Dot Org | 22 Apr 2025Researchers at the University of Oxford have developed a new...
New ultrasound drug delivery system found to be highly effective against bacterial biofilms (University of Oxford)
Public Technologies | 22 Apr 2025) Global healthHealthInnovationMathematical, Physical and Life SciencesMedical SciencesResearchScience Researchers at the University of...